Risk Factors

Bladder cancer is a type of cancer that begins in the cells of the bladder, the hollow organ in the pelvis responsible for storing urine before it's expelled from the body. Bladder cancer typically originates in the inner lining of the bladder known as the urothelium, although it can also develop in other types of bladder cells.

of bladder cancer




Cigarette smoking is the leading cause of bladder cancer, responsible for a significant portion of cases. The harmful chemicals in tobacco smoke can enter the bloodstream and accumulate in the bladder, increasing the risk of cancerous cell growth.

exposure to carcinogen


Certain occupations involve exposure to chemicals and substances known to increase the risk of bladder cancer. These include aromatic amines used in industries such as dye manufacturing, rubber production, and certain types of printing.

Chemical exposure


Exposure to certain chemicals, such as arsenic and chemicals used in the production of plastics, textiles, and paints, may increase the risk of bladder cancer.

bladder inflammation


Conditions that cause chronic irritation and inflammation of the bladder, such as recurrent urinary tract infections, bladder stones, and long-term use of urinary catheters, can increase the risk of bladder cancer.

Family history


Individuals with a family history of bladder cancer may have an increased risk of developing the disease, suggesting a possible genetic predisposition.



Bladder cancer becomes more common as people age, with the majority of cases diagnosed in individuals over the age of 55.



Men are more likely than women to develop bladder cancer, although the reasons for this difference are not entirely understood.

Race and ethnicity


Bladder cancer rates vary among different racial and ethnic groups, with higher incidence rates reported in Caucasians compared to African Americans and Asian Americans.

Chronic bladder infections


Chronic or recurrent urinary tract infections may increase the risk of bladder cancer, although the exact relationship between the two is not fully understood.

Exposure to radiations


Previous radiation treatment for other cancers, such as radiation therapy for prostate cancer or pelvic radiation for gynecologic cancers, may slightly increase the risk of bladder cancer later in life.