Modification of Diet in Renal Disease

Rahul priydarss

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What is MDRD?

The Modification of Diet in Renal Disease (MDRD) approach is a dietary strategy designed to slow the progression of chronic kidney disease (CKD).

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Why It Matters

Kidneys filter waste from blood. In CKD, this function weakens—diet modification reduces the workload on kidneys and delays complications.

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Protein Restriction

Too much protein stresses the kidneys. MDRD recommends controlled protein intake, usually 0.6–0.8 g/kg/day, depending on CKD stage.

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Sodium Control

High sodium = high blood pressure = kidney damage. The diet emphasizes low-salt meals to maintain fluid balance and protect kidney function.

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Phosphorus Limitation

Excess phosphorus weakens bones in CKD. MDRD suggests avoiding processed foods, cola, and dairy excess, while balancing with medical advice.

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Potassium Monitoring

Potassium can build up in CKD, leading to heart issues. MDRD requires individualized potassium control some patients restrict, others may not.

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Fluid Balance

Fluid overload causes swelling and hypertension. MDRD focuses on fluid intake guidance to reduce strain on kidneys and the heart.

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Calorie Adequacy

Even with restricted protein, MDRD ensures enough calories from carbs and healthy fats to prevent malnutrition and muscle loss.

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Individualized Approach

The diet isn’t one-size-fits-all. MDRD is personalized based on CKD stage, lab reports, and patient health status.

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Medical Supervision

MDRD should always be followed under the guidance of a nephrologist and renal dietitian—DIY diet changes may be risky in kidney disease.

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